1–2 ml EDTA blood or 1–2 µg genomic DNA. Alternative material must be confirmed before collection or shipment.
PREVENTION · PRV04
Iron & Copper Storage Prevention
Assesses genes associated with hereditary hemochromatosis, Wilson disease, aceruloplasminemia, and related iron-handling disorders.
Targeted next-generation sequencing of the complete coding sequence and relevant splice regions of the selected genes; this is not a hotspot-only screen.
Clinically classified findings, an explanation of the inherited risk, and recommendations for medical follow-up or preventive discussion.
Confirmed after case and sample review.
CLINICAL VALUE
Where this test is strongest
✓8 genes across iron and copper metabolism
✓Includes HFE and ATP7B
✓May support earlier biochemical monitoring
✓Can guide targeted family testing
LIMITATIONS
What must remain visible
!A predisposition is not a diagnosis and does not predict if or when disease will occur.
!A negative result does not remove all inherited or non-genetic risk; selection and interpretation require medical context.
GENE & ANALYTICAL SCOPE
8 published genes
Complete 8-gene storage-disorder scope.
Iron & copper storagePRV04 · 8 published genes+
Complete panel scope (8 genes).
ATP7BCPGLRX5HAMPHFEHJVSLC40A1TFR2
BEFORE ORDERING
Confirm the current laboratory specification.
The official case review and quotation confirm eligibility, accepted material, validated coverage and variant classes, consent, turnaround, price, and report pathway.