1–2 ml EDTA blood or 1–2 µg genomic DNA. Alternative material must be confirmed before collection or shipment.
PREVENTION · PRV02
Cardiovascular Disease Prevention
A broad preventive module spanning genes for inherited rhythm disorders, cardiomyopathies, thoracic aortic disease, and selected pulmonary vascular conditions.
Targeted next-generation sequencing of the complete coding sequence and relevant splice regions of the selected genes; this is not a hotspot-only screen.
Clinically classified findings, an explanation of the inherited risk, and recommendations for medical follow-up or preventive discussion.
Confirmed after case and sample review.
CLINICAL VALUE
Where this test is strongest
✓56 cardiovascular genes
✓Multiple clinically important disease groups
✓Can support targeted cardiac surveillance
✓May clarify risk for relatives
LIMITATIONS
What must remain visible
!A predisposition is not a diagnosis and does not predict if or when disease will occur.
!A negative result does not remove all inherited or non-genetic risk; selection and interpretation require medical context.
GENE & ANALYTICAL SCOPE
56 published genes
Broad 56-gene cardiovascular predisposition scope.
Cardiovascular diseasesPRV02 · 56 published genes+
Complete panel scope (56 genes).
ACTA2ACTC1ACVRL1ALPK3BAG3BMPR2CALM1CALM2CALM3CASQ2CAV1COL3A1DESDSC2DSG2DSPEMDENGFBN1FHL1FLNCGDF2KCNH2KCNK3KCNQ1KDRLAMP2LMNALOXMYBPC3MYH11MYH7MYL2MYL3MYLKPKP2PLNPRKAG2RBM20RYR2SCN5ASMAD3SMAD9TBX4TECRLTGFB2TGFBR1TGFBR2TMEM43TNNC1TNNI3TNNT2TPM1TRDNTTNTTR
BEFORE ORDERING
Confirm the current laboratory specification.
The official case review and quotation confirm eligibility, accepted material, validated coverage and variant classes, consent, turnaround, price, and report pathway.